The Lexus RX 350 manual provides comprehensive guidance for 2022 and newer models, detailing features, operation, and maintenance. It ensures optimal performance and safety.

1.1 Overview of the Lexus RX 350 Model
The Lexus RX 350 is a luxury SUV known for its refined design, powerful performance, and advanced features. It combines a spacious interior with a robust 3.5L V6 engine, offering smooth acceleration and responsive handling. Available in various trims, the RX 350 caters to diverse preferences, from comfort-focused models to sport-oriented versions. Its fuel efficiency and eco-friendly options make it a practical choice for daily driving. With a reputation for reliability and durability, the RX 350 is a popular choice in the luxury SUV segment, supported by comprehensive manuals for optimal ownership experience.
1.2 Importance of the Owner’s Manual
The Lexus RX 350 owner’s manual is essential for understanding vehicle features, troubleshooting, and maintaining optimal performance. It provides detailed instructions for operating advanced systems, ensuring safety, and extending the vehicle’s lifespan. The manual covers everything from basic controls to complex settings, helping owners make informed decisions. Regularly referencing the manual can prevent errors, reduce repair costs, and enhance driving experiences. Available in PDF format, it’s a vital resource for both new and experienced owners, offering clear guidance for every aspect of RX 350 ownership.
Table of Contents
The manual includes detailed sections on safety, operation, maintenance, interior features, performance, and customization, providing a comprehensive guide for Lexus RX 350 owners.
2.1 Structure of the Manual
The Lexus RX 350 manual is organized into clear sections, starting with an overview of the vehicle, followed by safety information, operating instructions, and maintenance guidelines. It includes detailed chapters on interior features, performance specifications, and advanced technology systems. The manual also covers customization options and warranty details, ensuring owners can easily navigate and find relevant information. Each section is designed to provide concise, user-friendly guidance, making it accessible for both new and experienced drivers to understand and utilize their vehicle effectively.
2.2 Key Sections to Focus On
Key sections of the Lexus RX 350 manual include safety features, operating instructions, and maintenance schedules. The manual emphasizes understanding warning lights and indicators for optimal vehicle performance. It also highlights essential maintenance routines, such as oil changes and tire rotations, to ensure longevity. Additionally, sections on advanced technology, like the infotainment system and driver-assistance features, provide detailed guidance. Customization options and warranty information are also covered, helping owners personalize and protect their vehicle. These sections are designed to enhance the driving experience and ensure proper care of the RX 350.

Safety Information
The Lexus RX 350 manual highlights critical safety features, warning lights, and emergency procedures. It ensures drivers understand indicators and precautions for secure operation and maintenance.
3.1 Safety Precautions
The Lexus RX 350 manual emphasizes essential safety precautions to ensure driver and passenger well-being. Always wear seatbelts, as they significantly reduce injury risk. Airbags are designed to deploy in collisions, but proper usage of seatbelts is crucial for optimal protection. Avoid overheating by not leaving children or pets unattended in the vehicle. Be cautious of hot surfaces, such as the engine or exhaust, after driving. Additionally, ensure proper fueling procedures to prevent fire hazards. Regularly check tire pressure and brakes for safe operation. Consult the manual for specific guidelines tailored to your vehicle.
3.2 Warning Lights and Indicators
The Lexus RX 350 manual details various warning lights and indicators to alert drivers of potential issues. The dashboard features symbols for engine malfunctions, low fuel, and system errors. Understanding these indicators is crucial for timely maintenance and safety. For instance, the check engine light signals engine-related problems, while the low fuel indicator alerts when fuel levels are critical. Refer to the manual for specific meanings and recommended actions. Regularly monitoring these lights ensures optimal vehicle performance and prevents costly repairs. The Lexus Display Audio system also provides visual and audible alerts for driver assistance;
Operating the Vehicle
Learn to start the engine, use the transmission, and engage driving modes. The manual provides tips for smooth operation, ensuring optimal performance and safety on the road.
4.1 Ignition and Starting the Engine
To start the Lexus RX 350, ensure the SmartAccess key is inside the vehicle. Press the ignition button firmly while braking. The engine will roar to life smoothly. Always refer to the manual for proper starting procedures to ensure safety and optimal performance. Adjust settings like climate control and audio before driving for a comfortable experience. The manual provides detailed guidance for a seamless start every time, ensuring your journey begins effortlessly.
4.2 Transmission and Gear Shift
The Lexus RX 350 features an 8-speed automatic transmission, designed for smooth acceleration and fuel efficiency. Use the shift lever to select modes: Park (P), Reverse (R), Neutral (N), or Drive (D). For manual control, paddle shifters allow gear changes without moving the lever. Always ensure the vehicle is stationary when shifting to Park. The manual provides detailed instructions for proper transmission operation, ensuring safe and efficient driving. Familiarize yourself with these controls to enhance your driving experience and maintain optimal performance.
4.3 Driving Modes and Settings
The Lexus RX 350 offers multiple driving modes to enhance your experience. Normal mode balances performance and efficiency, while Sport mode sharpens throttle response for dynamic driving. ECO mode prioritizes fuel efficiency by optimizing engine and climate control settings. Additional modes like Snow and Custom allow tailored driving experiences. Use the mode selector dial or buttons to switch between settings. The manual details how to activate and adjust these modes for optimal performance in various conditions. Familiarize yourself with these options to customize your driving experience and maximize comfort and efficiency.
Maintenance and Servicing
Regular maintenance ensures optimal performance and longevity. Schedule services at recommended intervals, follow DIY tips, and address common issues promptly for reliable operation and efficiency.
5.1 Scheduled Maintenance Intervals
Regular maintenance is crucial for the Lexus RX 350’s longevity. Follow the recommended schedule, typically every 5,000 to 7,500 miles, for oil changes and tire rotations. Inspections of belts, fluids, and brakes should occur at specified intervals to prevent wear. Refer to the owner’s manual for detailed timelines and procedures. Adhering to these intervals ensures optimal performance, fuel efficiency, and safety, while preventing costly repairs. Proper maintenance also preserves the vehicle’s warranty and resale value, keeping your Lexus running smoothly for years.
5.2 DIY Maintenance Tips
Performing routine DIY maintenance on your Lexus RX 350 can enhance its performance and longevity. Regularly check and top off fluids, such as engine oil, coolant, and windshield washer fluid. Inspect and replace the air filter every 15,000 to 30,000 miles to improve fuel efficiency. Check tire pressure monthly and rotate tires every 5,000 miles for even wear. Additionally, clean the battery terminals to prevent corrosion and ensure reliable starts. These simple tasks can be done at home, saving time and money while keeping your vehicle in optimal condition.
5.3 Troubleshooting Common Issues
Identifying and addressing common issues in your Lexus RX 350 can prevent major repairs. Check for warning lights on the dashboard, as they indicate specific problems. Low fuel efficiency may result from improper tire pressure or a dirty air filter. If the engine light illuminates, use an OBD-II scanner to diagnose the issue. Addressing oil leaks promptly can prevent engine damage. For unusual noises or vibrations, inspect the suspension and exhaust system. Regularly updating software and ensuring all systems are functioning correctly will help maintain your vehicle’s performance and reliability over time.

Interior Features
The Lexus RX 350 boasts a luxurious interior with premium materials, featuring an intuitive infotainment system, climate control, and comfortable seating options for enhanced driver and passenger comfort.
6.1 Infotainment System
The Lexus RX 350 features an advanced infotainment system with a high-resolution touchscreen display. It supports voice command, Bluetooth connectivity, and smartphone integration via Apple CarPlay and Android Auto. The system includes navigation, USB ports, and a premium audio setup for an enhanced driving experience. Drivers can customize settings and access various apps seamlessly. The manual provides detailed instructions for operating and troubleshooting the infotainment system, ensuring optimal functionality and user satisfaction.
6.2 Climate Control and Comfort
The Lexus RX 350 offers a dual-zone automatic climate control system, allowing driver and passenger to set individual temperatures. The climate concierge feature automatically adjusts settings for optimal comfort. The system includes an air quality sensor and rear-seat vents for enhanced circulation. The manual provides instructions for operating the climate control, including setting temperatures, airflow direction, and activating the air purification mode. This ensures a comfortable driving experience in all conditions, with intuitive controls and advanced features designed for passenger well-being.
6.3 Seating and Storage Options
The Lexus RX 350 features premium leather-trimmed seats with power adjustments, heating, and ventilation for optimal comfort. The second row offers reclining and sliding functions, while optional third-row seating provides versatility. The manual details how to fold seats for maximum cargo space, with a 40/20/40 split-folding second row and power-folding third row. Additional storage includes a spacious cargo area, door pockets, and a center console. These features ensure ample space for passengers and luggage, making the RX 350 ideal for both daily commutes and long trips.

Exterior Features
The Lexus RX 350 boasts a sleek, aerodynamic design with LED headlights, alloy wheels, and a power moonroof. Its exterior combines luxury with practicality, offering versatility.
7.1 Design and Aerodynamics
The Lexus RX 350 features a sleek, aerodynamic design with sharp lines and a bold grille. LED headlights and alloy wheels enhance its premium look. The power moonroof adds convenience and style. Aerodynamic elements like air intakes and spoilers improve airflow, reducing drag for better efficiency. Lightweight materials contribute to agility and performance. The design balances luxury and functionality, ensuring a smooth driving experience while maintaining a sophisticated appearance. These features collectively enhance both visual appeal and aerodynamic efficiency, making the RX 350 a standout in its class.
7.2 Wheels and Tires
The Lexus RX 350 comes with standard 18-inch alloy wheels, offering a balance of style and durability. Optional 20-inch alloy wheels are available for enhanced aesthetics and performance. The vehicle is equipped with all-season tires, designed for versatility across various driving conditions. Summer tires are also an option for improved grip and handling on dry roads. Proper tire pressure, as specified in the manual, ensures optimal fuel efficiency and safety. Regular tire rotations and inspections are recommended to maintain even wear and extend lifespan. The Tire Pressure Monitoring System (TPMS) alerts drivers to low pressure, enhancing safety on the road.

7.3 Exterior Accessories
The Lexus RX 350 offers a range of exterior accessories to enhance functionality and style. Optional roof racks provide additional storage for luggage or sports equipment, while side steps and running boards improve accessibility. Mudguards protect the vehicle from debris, and chrome or alloy wheel locks add a touch of elegance and security. Exterior trim kits and spoilers can also be added to personalize the vehicle’s appearance. These accessories are designed to complement the RX 350’s sleek design while offering practical benefits for everyday use or adventurous trips.

Performance and Specifications
The Lexus RX 350 features a powerful 3.5L V6 engine, delivering 295 horsepower and 267 lb-ft of torque. It offers smooth performance with an 8-speed automatic transmission and optional all-wheel drive, ensuring responsive handling and stability. The vehicle achieves an estimated 27 MPG highway and 20 MPG city, balancing power with efficiency for a refined driving experience.
8.1 Engine and Powertrain
The Lexus RX 350 is equipped with a 3.5L V6 engine, producing 295 horsepower and 267 lb-ft of torque. Paired with an 8-speed automatic transmission, it ensures smooth acceleration and responsive performance. The engine features Dual Variable Valve Timing with Intelligence for enhanced efficiency and power delivery. Available all-wheel drive optimizes traction and stability, while the rear-wheel-drive model offers improved fuel economy. This powertrain combination provides a balance of strength and refinement, making it suitable for both city driving and highway cruising.
8.2 Fuel Efficiency and Economy
The Lexus RX 350 offers impressive fuel efficiency, with an EPA rating of 20 mpg combined (18 city, 25 highway) for the front-wheel-drive model. The all-wheel-drive version slightly lowers these numbers to 19 mpg combined (18 city, 24 highway). The 3.5L V6 engine is designed for optimal balance between power and economy. Regular unleaded gasoline (87 octane) is recommended for best performance. With a 19.2-gallon fuel tank, the RX 350 provides a comfortable range for long drives, making it a practical choice for both daily commuting and extended trips.
8.3 Handling and Suspension
The Lexus RX 350 features a refined suspension system designed for both comfort and responsiveness. It utilizes a MacPherson strut front suspension and a multi-link rear suspension, ensuring a smooth ride while maintaining precise handling. The Adaptive Variable Suspension (AVS) system is available, allowing real-time damping adjustments to road conditions. This enhances stability and reduces body roll during cornering. The electric power steering provides crisp feedback, making the RX 350 agile and easy to maneuver. Together, these components deliver a balanced driving experience, blending luxury with dynamic performance.
Technology and Innovation
The Lexus RX 350 manual highlights advanced driver-assistance systems, including adaptive cruise control and lane-keeping assist. It also features a touchscreen infotainment system with navigation and smartphone integration.
9.1 Advanced Driver-Assistance Systems
The Lexus RX 350 manual details its suite of advanced safety features, including adaptive cruise control, lane departure warning, and automatic emergency braking. These systems enhance driver confidence and reduce collision risks. The manual explains how to activate and customize these features, ensuring seamless integration with the vehicle’s operation. Proper understanding of these technologies is crucial for maximizing safety and driving efficiency, as outlined in the guide.
9.2 Navigation and Connectivity
The Lexus RX 350 manual highlights the vehicle’s advanced navigation and connectivity features, including the intuitive Lexus Display Audio system. Drivers can seamlessly integrate smartphones via Apple CarPlay® and Android Auto™, enabling voice-command navigation and app control. The system also supports wireless charging, ensuring convenient device charging on the go. The manual provides step-by-step guidance on setting up and using these features, enhancing the overall driving experience with modern connectivity solutions.
9.3 SmartAccess and Keyless Systems

The Lexus RX 350 manual details the SmartAccess keyless entry system, allowing drivers to unlock and start the vehicle without a physical key. The system uses a proximity sensor in the door handles and a push-button start. It also includes a remote touch interface for intuitive control. The manual explains how to pair keys, troubleshoot issues, and customize settings for enhanced convenience and security. This feature ensures a seamless and modern driving experience, aligning with Lexus’s commitment to innovation and user-friendly technology.

Customization and Accessories
The Lexus RX 350 manual highlights various customization options and genuine accessories, enabling owners to personalize their vehicle. Accessories include trim kits, alloy wheels, and cargo solutions.
10.1 Personalizing Your RX 350
Personalizing your Lexus RX 350 enhances its appeal and functionality. Owners can choose from a variety of interior trim options, such as wood or aluminum accents, to match their style. Exterior customization includes alloy wheel designs and paint finishes. Additionally, tech features like customizable infotainment settings and driver preferences can be tailored for a unique experience. The manual provides guidance on compatible accessories and modifications, ensuring personal touches align with the vehicle’s performance and design integrity.
10.2 Available Aftermarket Accessories
The Lexus RX 350 supports a wide range of aftermarket accessories to enhance its functionality and style. Owners can opt for exterior upgrades like alloy wheels, roof racks, and body kits. Interior accessories include premium seat covers, cargo organizers, and ambient lighting. Performance enhancements, such as air filters and exhaust systems, are also available. Additionally, tech accessories like wireless charging pads and smartphone integration kits can be installed. These accessories are designed to complement the vehicle’s design and performance while maintaining compatibility and warranty standards.
Warranty and Support
Lexus offers a comprehensive warranty program for the RX 350, including basic and powertrain coverage. Dedicated customer support and service centers ensure optimal assistance and maintenance.
11.1 Manufacturer Warranty Details
The Lexus RX 350 comes with a comprehensive manufacturer warranty, including a 4-year/50,000-mile basic warranty and a 6-year/70,000-mile powertrain warranty. Additional coverages include corrosion protection and emissions warranties. These warranties ensure long-term reliability and peace of mind for owners, covering essential components and repairs. Lexus also offers roadside assistance and maintenance plans to enhance ownership experience. The warranties are transferable, adding value if the vehicle is sold. Detailed terms and conditions are outlined in the owner’s manual for clarity and reference.
11.2 Customer Support and Service Centers
Lexus offers exceptional customer support through its extensive network of authorized service centers. Trained technicians ensure high-quality maintenance and repairs, adhering to factory standards. Owners can access online resources, including service scheduling and warranty details. The brand’s reputation for reliability is supported by 24/7 roadside assistance and dedicated customer care. Service centers provide genuine parts and transparent pricing, ensuring trust and satisfaction. Regular maintenance programs and exclusive offers further enhance the ownership experience, making Lexus a leader in customer-centric care.

Environmental Impact
The Lexus RX 350 emphasizes eco-friendliness with reduced emissions and improved fuel efficiency, aligning with sustainability goals while maintaining performance and luxury standards.
12.1 Emissions and Eco-Friendliness
The Lexus RX 350 is designed to minimize environmental impact through reduced emissions and enhanced fuel efficiency. Its advanced engine and hybrid powertrain options lower emissions while maintaining performance. The vehicle incorporates technologies like direct fuel injection and optimized exhaust systems to further reduce its carbon footprint. By meeting strict emissions standards, the RX 350 supports eco-friendly driving. Additionally, features such as eco-driving modes and efficient energy management contribute to sustainability. Lexus prioritizes environmental responsibility without compromising on luxury or power.
12.2 Fuel Efficiency and Sustainability
The Lexus RX 350 emphasizes fuel efficiency and sustainability through its optimized powertrain and eco-friendly design. With an estimated EPA rating of up to 27 MPG combined, it balances performance and economy. The 3.5L V6 engine and 8-speed automatic transmission ensure smooth, efficient power delivery. Eco driving modes further enhance fuel savings by adjusting engine and climate control settings. Lexus’s commitment to sustainability is evident in its lightweight construction and advanced technologies, reducing environmental impact while maintaining luxury and reliability.
The Lexus RX 350 manual is an essential guide for owners, offering detailed insights to maximize performance, safety, and longevity. Referencing it ensures optimal vehicle operation and maintenance.
13.1 Summary of Key Points
The Lexus RX 350 manual is a detailed guide covering features, operation, and maintenance. It emphasizes performance, safety, and customization options. Key points include engine specifications, advanced safety technologies, and maintenance schedules. The manual also highlights fuel efficiency, interior comforts, and exterior design elements. Regular servicing and DIY tips are provided to ensure longevity. Understanding the manual enables owners to optimize their driving experience and maintain the vehicle’s premium condition. Referencing it regularly ensures safety, efficiency, and overall satisfaction with the Lexus RX 350.
13.2 Final Tips for Optimal Use
Regularly review the manual to stay updated on features and maintenance. Familiarize yourself with advanced safety systems and driving modes for enhanced control. Schedule routine servicing to maintain performance and longevity. Customize settings to personalize your driving experience. Keep the manual handy for quick reference during trips or unexpected issues. By following these tips, you can maximize the potential of your Lexus RX 350 and enjoy a safe, comfortable, and efficient driving experience.